PhD defence and trial lecture: Youngjin Park (FBA)

Doctoral candidate Youngjin Park will hold a trial lecture and defend his thesis for the degree Philosophiae Doctor (PhD) at the Faculty of Biosciences and Aquaculture (Bodø), Nord University.

Start date:

29 January 2021 14:00

End date:

29 January 2021 18:50

Location:

Teams & A13 Elias Blix
​​​​​​​​​​​​​​​Follow the defence via Teams here
​​

Doctoral candidate: Youngjin Park

Trial lecture topic
Intestinal macrophages in homeostatic and pathological states

Thesis title
Transcriptomic and cellular studies on the intestine of Atlantic salmon: Discovering intestinal macrophages using omic tools​

Evaluation Committee
- Associate Professor Irene Salinas, Department of Biology, University of New Mexico, USA
- Professor Rune Waagbø, Institute of Marine Research, Bergen
- Researcher Alexander Jüterbock FBA, Nord University

Supervisory Committee
- Professor Kiron Viswanath, FBA, Nord University
- Professor Jorge Fernandes, FBA, Nord University
- Professor Geert Wiegertjes​, Wageningen University & Research, the Netherlands

About the thesis
Intestine is the primary site where the interaction among dietary components, microbiota and immune system takes place. There is not much knowledge regarding the intestinal cells of teleosts, including Atlantic salmon. This thesis focuses on characterization of certain cell types and inflammatory responses in the intestine of salmon.  

In this study, imaging flow cytometry technique was used to examine the size and complexity of cells and their functions. Protocols were first optimized to examine the intestinal immune cells and study their phagocytic activity. Flow cytometry and transcriptomic analyses revealed diverse cells which included macrophages, epithelial cells and endothelial cells in salmon intestine. In addition, feed ingredient-induced inflammation and the associated disturbances in ion transport and metabolic pathways are also described in this thesis.

Future studies, particularly on the macrophage population would cast light on how these cells participate in intestinal immune defence. Furthermore, the findings from this study could be exploited to investigate the responses of the intestinal cells to various stimuli and eventually use them for establishing indices for gut health in farmed fish.​​

Trial lecture: 14:00 - 15:00
Thesis defence: 16:10 - 18:50

All participants engaging remotely via Teams are advised to​ turn off their cameras and microphones for the duration of the trial lecture and thesis defence.


Start date:

29 January 2021 14:00

End date:

29 January 2021 18:50

Location:

Teams & A13 Elias Blix
The PhD trial lecture and defence are open to the public. The thesis is available upon request. Please contact Jeanett Stegen.​​