Current active subject description (last updated 2024/25)
RNA Biology
BI322F
Current active subject description (last updated 2024/25)
RNA Biology
BI322F
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Genomic analyses strongly indicate that genetic complexity scales with RNA-based regulation. But what makes RNA unique compared to DNA? This course focus on RNA versatility, from molecular architecture to cellular functions and biological roles. Topics include RNA structure and catalysis, mRNA intron splicing, RNA processing and translation, non-coding RNAs, and RNA in research.
For students admitted to Master in Biosciences or PhD in Biosciences at Nord University.
Knowledge
The student should:
- Have theoretical knowledge of major aspects of RNA biology, which includes RNA structure, cellular function and biological role
- Understand: i) RNA from sequence to 3-dimentional structure ii) the catalytic properties of RNA; iii) how the spliceosome and ribosome works; iv) maturation and stability of cellular RNA; v) RNA editing and nucleotide modification; vi) how short and long non-coding RNA works; vii) future prospective in RNA biology
- Understand why and how RNA biology could be applied genomic research
Skills
The student should:
- Read and understand up-front scientific literature on RNA biology
- Document and communicate new scientific results
General competence The student should:
- Communicate what RNA molecules are, why it is important to investigate RNA, and how studies can be designed and performed
No tuition fees. Semester fees and cost of course literature and laptop apply.In addition to the semester fee and syllabus literature, students are expected to have a laptop with microphone and camera. Students must purchase their own laboratory coat for use in courses with laboratory exercises.
Specialization - Master in Biosciences - Genomics
Elective - Master in Biosciences
Lectures (20h) Questions/discussion colloquium (4h) Obligatory research seminar (8h)
Evaluation using mid-term and final surveys. Students are also encouraged to participate in the central quality surveys.
Compound evaluation, grading scale Letter grades
- Assessments Task , comprises 0/100 of the grade, grading scale Approved/ Not approved.
- Oral examination, comprises 100/100 of the grade, grading scale Letter grades.
Previous knowledge in molecular biology corresponding to BI122F (Genetics and Evolution) (10 ECTS) and BI210F (Molecular Cell Biology).