Subject description for 2024/25
Medicinal Chemistry
FAR2015
Subject description for 2024/25

Medicinal Chemistry

FAR2015
Medicinal Chemistry focuses on molecular mechanisms of action of active pharmaceutical ingredients, structural activity relationships (SAR), the key principles of pharmacokinetics from a chemical perspective and the structure of a range of pharmaceutically relevant natural substances. These topics are illustrated by using selected main groups of pharmaceuticals.
The course deals with the chemistry of pharmaceutical substances and how the chemical properties of pharmaceuticals affect their biological profiles. The course deals with topics such as basic pharmaceutical principles, stability and structural activity conditions in respect of the main groups of pharmaceuticals. The course also covers natural substance chemistry and provides an introduction the structure and activities of the most important natural substance classes of a range of biologically important molecules.
The course is reserved for students in the Bachelor's Programme in Pharmacy.
Students must have passed all courses during the first semester in order gain access to course teaching.

Knowledge

The student

  • has broad knowledge of the general principles which apply to medicinal chemistry and specific knowledge of

medicinal chemistry relating to the most commonly used groups of pharmaceuticals

  • has knowledge of how pharmaceuticals affect different target structures such as receptors, enzymes, ion channels and transport proteins
  • has knowledge of how pharmaceuticals are metabolised in the body
  • has in-depth knowledge of how the physiochemical properties of active ingredients affect solubility and absorption
  • has knowledge of the structure, properties and application of selected pharmaceutically relevant natural substances
  • has an overview of the basic techniques used in the development of pharmaceuticals

Skills

The student

  • is able to identify the physiochemical properties of active ingredients on the basis of their structure
  • is able to apply chemical principles in respect of a range of active ingredients, which is important for their effects and stability

General competence

The student

  • is able to, on the basis of pharmaceutical information, to account for topics that relate directly to chemicals and is also able to participate actively in discussions about other topics where these might be related to the structure and chemical properties of the pharmaceutical substances
In addition to the semester fees and course literature, students are expected to provide their own laptops, web cameras and headphones.

Theoretical course

Only students admitted to the Bachelor's Programme in Pharmacy are given the option to take this course. Compulsory

Teaching takes place on campus. Some teaching may be done online. The following learning activities are used during teaching: lectures and seminars. It is required that students themselves become actively involved in their learning process. Individual work accounts for a high percentage of the course workload.

course attendance is compulsory. Compulsory attendance is necessary for ensuring that students achieve the learning outcomes described for the course.

Compound assessement, grading scale A - F.All parts described below must be approved/passed in order to receive a final grade in the course.

  • Compulsory participation - 80%, comprises 0/100 of the grade, grading scale Approved/ Not approved.
  • Written school examination, 4 hours, grading scale A - F.
  • Approved calculator
  • Pen, ruler and up to 2 bilingual dictionaries