Molecular Biology of RNA
Genome studies indicate that the genetic complexity scales with RNA-based regulation. But what makes RNA unique compared to DNA at molecular and cellular levels? This course focus on RNA versality, from the molecular architecture and cellular functions to biological roles and diseases. The course includes topics like RNA structure and catalysis, RNA intron splicing, RNA processing, RNA stability and translation, RNA modification and editing, RNA viruses and vaccines, regulatory RNA, and the role of transcriptomes in recent research.
The course is organized in three parts. Part 1 consists of lectures and discussions, estimated to 30 hours, and self-study to 30 hours. Part 2 consists of a written assignment of a given topic in RNA biology, estimated to at least 40 hours. Part 3 consists of an oral presentation in plenum based on a selected review paper, estimated to a least 20 hours. Total workload estimated to approximately 150 hours including exam preparations.
Knowledge
The candidate should:
· Be at the forefront of knowledge within the academic field of molecular biology of RNA
· Have theoretical knowledge of major aspects of RNA biology, which include molecular RNA structures, cellular functions, and biological roles
· Be able to understand and communicate molecular aspects of RNA biology
· Be able of judging the implications of research methods and processes, and to understand why and how RNA biology could be applied in genomic research
Skills
The candidate should:
· Read and understand up-front reviews and research literature on the molecular biology of RNA
· Develop new research questions and topics in the field of RNA biology
· Discuss complex academic questions and challenge the established knowledge
· Document and communicate new scientific results in the field of RNA biology in written and oral forms
General competence
The candidate should:
· Be able to disseminate and communicate the research field of RNA biology through appropriate national and international channels to ensure knowledge-sharing with the community at large
· Be able to communicate what RNA molecules are, and why it is important to further investigate RNA, and how studies can be designed and performed
· Be able to engage in debates on RNA-related topics in relevant forums
· Share knowledge and protect it where necessary following internationally accepted guidelines and regulations
Dialogue between student and main supervisor. Annual evaluations that are included in the
Nord University quality assurance system.
Written assignment and oral presentations in plenum, which must be approved prior to submission for oral exam. Grading scale: Approved/ Not Approved.
Oral examination. The oral exam will cover all course topics and the written assignment. External evaluator. Grading scale: Passed/ Not Passed.
